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SmartDrop Nano SpectroPhotometers

Microvolume Analysis of DNA, RNA and Proteins

SmartDrop™ Nano Spectrophotometers

Microvolume Analysis of DNA, RNA and Proteins

Quick and accurate results from a sample droplet
Touch screen control panel, no PC or software required
Built-in printer and cuvette port for OD600 readings
XF model includes fluorometer for sensitive DNA quantification

The Accuris SmartDrop™ series of nano spectrophotometers provides quick and easy quantification of small samples. Utilizing a small sample volume eliminates the need for dilutions, providing more accurate results.

A full color, 7” touchscreen with icon-driven menus and preprogrammed protocols gets users up and running quickly. No external computer is required. Each unit features a quartz pedestal onto which a drop of sample is placed. The arm is lowered and the drop is stretched into a liquid column of specificed length for spectral analysis. DNA, RNA and protein concentrations and purity numbers are displayed in a matter of seconds.

The resulting data can be printed, saved in the SmartDrop’s onboard memory or exported via USB as an Excel file. All SmartDrop™ models include an integrated printer. For OD600 readings, each model includes a cuvette port and two optical glass cuvettes. Three SmartDrop™ models are available to meet a range of applications and budgets.

SmartDrop™ L

Ideal for basic DNA/RNA/protein quantification and purity
Affordable LED and silicon detector technology
Fixed 0.5mm path length, detect up to 2500ng/µL of dsDNA

SmartDrop™ L is the affordable choice for laboratories needing to determine nucleic acid and protein concentrations and purity of samples. The LED light source and silicon photocell sensor provide readings at 260 and 280nm. Samples from 1.0 to 2.0 µL are loaded directly on the pedestal. Results are provided in about 5 seconds. The software automatically calculates and displays 260/280 ratios.

SmartDrop™ X

Full-spectrum absorbance scans from 200 to 800nm
Quickly calculates and displays 260/280 and 260/230 ratios
Long-life Xenon lamp with precision monochromator
Auto-ranging path lengths of 0.2mm and 1.0mm
Detect up to 4,500 ng/µL of dsDNA without dilution

A full spectrum UV-Vis spectrophotometer, SmartDrop™ X requires 0.5 to 2.0 µL of sample. In addition to nucleic acid and protein calculations, the software has preset programs for BCA, Bradford and Lowry assays. A full spectrum analysis can be performed in about 6 seconds, aiding in the identification of unknowns. Up to 5 specific points on the spectrum can be selected for colorimetric readings output. The long life Xenon lamp source requires no warm up and is paried with a highly sensitive CCD detector. To provide the most accurate results, the SmartDrop™ X utilizes 2 path lengths.

SmartDrop™ XF – Spectrophotometer + Fluorometer

Full-spectrum absorbance scanning and calculations of 260/280 and 260/230 ratios
Long-life Xenon lamp with precision monochromator
Auto-ranging path lengths of 0.05mm, 0.2mm and 1.0mm
Detect up to 15,000ng/µl of dsDNA without dilution
Integrated fluorometer for sensitive quantitation of low concentration nucleic acids

This top of the line spectrophotometer can perform not only UV-Vis readings in the range of 200-800nm but also fluorescence readings. Like the SmartDrop™ X, the SmartDrop™ XF features predefined programs for nucleic acids, proteins, and various colorimetric assays. The patented, motorized system gently stretches the sample column and allows for three different path lengths, providing accurate readings of samples from 0.5 to 2.0 µL without dilution. The integrated fluorometer yields more accurate, sensitive and selective quantitation of nucleic acids. The blue light channel (460nm) is useful for detection of dyes such as PicoGreen and RiboGreen as well as GFP and fluorescein. UV, green and red channel models are available upon request.

Specifications

Model	SmartDrop™ L (NS1000)	SmartDrop™ X (NS1010)	SmartDrop™ XF (NS1020)
Display	7-inch touch screen	7-inch touch screen	7-inch touch screen
Minimum Sample Size	1.0 µL – 2.0 µL	0.5 µL to 2.0 µL	0.5 µL to 2.0 µL
Path Length	0.5mm	0.2mm, 1.0mm	0.05mm, 0.2mm, 1.0mm
Light Source	UV LED	Xenon Flash Lamp	Xenon Flash Lamp
Detector	UV Silicon Photocell	2048 Element Linear Silicon CCD Array	2048 Element Linear Silicon CCD Array
Wavelength	260, 280, & 600nm	200 – 800nm (1nm steps)	200 – 800nm (1nm steps)
Absorbance Range	0.2 – 50 A (10mm equivalent)	0.04 – 90 A (10mm equivalent)	0.04 – 300 A (10mm equivalent)
Absorbance Precision	0.005 A	0.003 A	0.003 A
Lower Limit of Detection	dsDNA: 10ng/µL	dsDNA: 2ng/µL; BSA: 0.1mg/mL	dsDNA: 2ng/µL ; BSA: 0.1mg/mL
Upper Limit of Detection	dsDNA: 2,500ng/µL	dsDNA: 4,500ng/µL; BSA: 135mg/mL	dsDNA: 15,000ng/µL; BSA: 360mg/mL
Detection Time	< 6 seconds	< 5 seconds	< 6 seconds
Communication Ports	USB for data export	USB for data export	USB for data export
Voltage Input	DC 24V, 2A	DC 24V, 2A	DC 24V, 2A
Power	25W	25W	25W
Dimensions (WxDxH)	20.8 x 8.0 x 18.6 cm / 8.2 x 11.0 x 7.3 in.	20.8 x 8.0 x 18.6 cm / 8.2 x 11.0 x 7.3 in.	20.8 x 8.0 x 18.6 cm / 8.2 x 11.0 x 7.3 in.
Weight	3.6 kg / 7.9 lbs	2.8 kg / 6.2 lbs	3.6 kg / 7.9 lbs
Absorbance Range	0.0 – 4.0 A	0.0 – 4.0 A	0.0 – 4.0 A
Absorbance Stability	[0,3) ≤ 0.5%, [3,4) ≤ 2%	[0,3) ≤ 0.5%, [3,4) ≤ 2%	[0,3) ≤ 0.5%, [3,4) ≤ 2%
Absorbance Repeatability	[0,3) ≤ 0.5%, [3,4) ≤ 2%	[0,3) ≤ 0.5%, [3,4) ≤ 2%	[0,3) ≤ 0.5%, [3,4) ≤ 2%
Absorbance Precision	[0,2) ≤ 0.005 A, [2,3) ≤ 1%, [3,4) ≤ 2%	[0,2) ≤ 0.005 A, [2,3) ≤ 1%, [3,4) ≤ 2%	[0,2) ≤ 0.005 A, [2,3) ≤ 1%, [3,4) ≤ 2%
Excitation/Emission	N/A	N/A	460 ± 20nm / 525-570nm
Sensitivity	N/A	N/A	dsDNA: 0.5pg/µL
Linearity	N/A	N/A	R² ≥ 0.995
Repeatability	N/A	N/A	≤ 1.5%
Stability	N/A	N/A	≤ 1.5%